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This phase I/II trial studies the safety, side effects, best dose, and effectiveness of adding a drug called blinatumomab to usual chemotherapy for treating *^The purpose of this study is to improve upon the TINI study treatment. The study will test the ability of a type of immunotherapy called blinatumomab to *$This study will enroll infants up to 1 year of age who have acute lymphoblastic leukemia (ALL). ALL is a cancer of the white blood cells.~If your child takes part in this study, they will receive multiple rounds of chemotherapy to achieve remission. Remission means there is no evidence of leukemia *"View eligibility and treatment information for TINI, a clinical trial for infants with acute lymphoblastic leukemia at St. Jude Childrens Research Hospital.%The purpose of this study is to improve upon the TINI study treatment. The study will test the ability of a type of immunotherapy called blinatumomab to clear *^The purpose of this study is to improve upon the TINI study treatment. The study will test the ability of a type of immunotherapy called blinatumomab to clear *